Factor | Plasma half-life | Hemostatic level* |
Fibrinogen | 2 to 4 days | 50 to 100 mg/dL |
Prothrombin (factor II) | 3 to 4 days | 20 to 30% |
Factor V | 36 hours | 15 to 20% |
Factor VII | 4 to 6 hours | 15 to 20% |
Factor X | 40 to 60 hours | 15 to 20% |
Factor XI | 40 to 70 hours | 15 to 20% |
Factor XIII | 11 to 14 days | 10 to 15% |
Factor V + factor VIII combined deficiency | 36 hours for factor V and 10 to 14 hours for factor VIII | 15 to 20%¶ |
Multiple vitamin K-dependent factor deficiencies (factors II, VII, IX, X) | Refer to individual factor half-lives above | 15 to 20% |
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