Disease | Presenting symptoms | Exacerbating factors | Most important screening tests | Treatment |
Porphyria cutanea tarda (PCT) | Chronic, blistering skin lesions* | Iron; alcohol; smoking; estrogens; hepatitis C; HIV; halogenated hydrocarbons | Plasma or urine porphyrins¶ | Phlebotomy; low-dose hydroxychloroquine or chloroquine |
Acute intermittent porphyria (AIP) | NeurovisceralΔ | Drugs (mostly cytochrome P450-inducers); progesterone; dietary restrictionsΔ | Urinary porphobilinogen (PBG)Δ | Hemin; glucoseΔ |
Erythropoietic protoporphyria (EPP) | Acute, nonblistering skin photosensitivity | Erythrocyte protoporphyrin (total and metal-free) | β-carotene; afamelanotide |
Do you want to add Medilib to your home screen?