Regimen | Incidence chemotherapy-induced amenorrhea according to age at treatment initiation (%) | |
<40 years | ≥40 years | |
CMF | 30 to 80 | 60 to 96 |
AC | 13 to 30 | 57 to 63 |
FEC/FAC | 10 to 25 | 80 to 90 |
AC followed by a single agent taxane | 15 to 42 | 66 to 77 |
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