Return To The Previous Page
Buy a Package
Number Of Visible Items Remaining : 3 Item

Solutions for standardized desensitization protocol (using an example of a target drug dose of 1000 mg)

Solutions for standardized desensitization protocol (using an example of a target drug dose of 1000 mg)
Solution Volume in mL Concentration Dose (mg) in solution
1 250 mL 0.04 mg/mL 10 mg
2 250 mL 0.4 mg/mL 100 mg
3 250 mL 4 mg/mL 1000 mg
The above three solutions are required for the standardized protocol for drug desensitizations for immediate hypersensitivity reactions. Solution 3 is the normal intravenous preparation of the drug as it is usually administered (ie, 1000 mg in 250 mL). Solution 2 is a 10-fold dilution of solution 3, and solution 1 is a 10-fold dilution of solution 2. Note that if the full amount of all three solutions were administered, a total of 1110 mg would be given. To avoid this, only part of solution 3 is infused.
Courtesy of Mariana Castells, MD, PhD.
Graphic 50123 Version 4.0

Do you want to add Medilib to your home screen?