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Version August 2025
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Criteria for outpatient anticoagulation in patients with pulmonary embolism
Criteria for outpatient anticoagulation in patients with pulmonary embolism
Low risk of death on PESI or sPESI
No oxygen requirement
No narcotic requirement
No respiratory distress
Normal pulse and blood pressure
No recent history of bleeding or risk factors for bleeding
No serious comorbid conditions
Normal mental status with good understanding of risk and benefits
Not needle averse (if low molecular weight heparin chosen)
Have good home support without barriers for discharge and reliable access to hospital
Absence of concomitant DVT
Ready access to DOACs
DOACs: direct oral anticoagulants; DVT: deep venous thrombosis; PESI: Pulmonary Embolism Severity Index; sPESI: simplified PESI.
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