Considerations when applying these criteria | |
| |
Clinical criteria | |
Obstructive airway disease | +3 |
Nasal polyps | +3 |
Mononeuritis multiplex | +1 |
Laboratory and biopsy criteria | |
Blood eosinophil count ≥1 × 109/liter | +5 |
Extravascular eosinophilic-predominant inflammation on biopsy | +2 |
Positive test for cytoplasmic antineutrophil cytoplasmic antibodies (cANCA) or antiproteinase 3 (anti-PR3) antibodies | –3 |
Hematuria | –1 |
Sum the scores for 7 items, if present. A score of ≥6 is needed for classification of eosinophilic granulomatosis with polyangiitis. |
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