Laboratory testing in hyperfibrinolytic states

Test	Typical finding in hyperfibrinolytic states
Complete blood count (CBC) and platelet count	Normal, unless there has been significant blood loss
Prothrombin time (PT) and activated partial thromboplastin time (aPTT)	Normal or prolonged
Fibrinogen	Low
Euglobulin clot lysis time (ECLT)	Shortened
Thromboelastography (TEG)	Increased clot lysis at 30 minutes (LY30)
Urea clot solubility (tests fibrin crosslinking)	Normal^*

Refer to UpToDate for a discussion of hyperfibrinolytic states and details of these tests.

* This test is abnormal in factor XIII deficiency (hereditary or acquired).

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