Drug name(s) | Preparation(s) | Dose |
Inhaled corticosteroid and short-acting beta-agonist (ICS-SABA) | ||
Albuterol-budesonide MDI* (Brand name [United States]: Airsupra) | MDI: Albuterol 90 mcg and budesonide 80 mcg/actuation |
|
ICS and formoterol combinationsΔ◊ | ||
Budesonide-formoterol MDI (Brand names [United States]: Symbicort, Breyna) | MDI: Budesonide 80 mcg and formoterol 4.5 mcg/actuation MDI: Budesonide 160 mcg and formoterol 4.5 mcg/actuation |
|
Budesonide-formoterol DPI§ (Brand name [Canada]: Symbicort Forte) | DPI: Budesonide 100 mcg and formoterol 6 mcg/actuation DPI: Budesonide 200 mcg and formoterol 6 mcg/actuation |
|
Mometasone-formoterol MDI (Brand names: Dulera [United States], Zenhale [Canada]) | MDI: Mometasone 100 mcg and formoterol 5 mcg/actuation MDI: Mometasone 200 mcg and formoterol 5 mcg/actuation |
|
Beclomethasone [beclometasone]-formoterol DPI§ or MDI (Not available in United States or Canada, but available elsewhere [sample brand names: Formodual, Fostair, Foster]) | DPI or MDI: Beclomethasone 100 mcg and formoterol 6 mcg/actuation DPI or MDI: Beclomethasone 200 mcg and formoterol 6 mcg/actuation |
|
Fluticasone propionate-formoterol MDI (Not available in United States or Canada, but available elsewhere [sample brand name: Flutiform]) | MDI: Fluticasone 50 mcg and formoterol 5 mcg/actuation MDI: Fluticasone 125 mcg and formoterol 5 mcg/actuation MDI: Fluticasone 250 mcg and formoterol 5 mcg/actuation |
|
AIR: anti-inflammatory reliever; DPI: dry powder inhaler; MDI: metered-dose inhaler.
* Not approved for use in patients <18 years old.
¶ Over the course of the first hour, the patient can determine (based on action plan or clinician guidance) whether to continue self-care at home or seek additional medical attention. When administering an MDI for acute asthma exacerbation, use of a valved holding chamber (for compatible MDIs) and careful attention to technique are recommended.
Δ Do not exceed the maximum number of inhalations per day due to the risk of toxicity from an excess dose of formoterol. Guidelines published by the Global Initiative for Asthma (GINA) recommend a maximum dose of 12 inhalations per day; however, in some countries, prescribing information includes a maximum dose of 8 inhalations per day.
◊ Evidence for AIR-only therapy is with budesonide-formoterol 200 mcg/6 mcg DPI inhalers. Other strengths or formulations may be used based on local product availability or as part of maintenance and reliever therapy (MART). Refer to related table for more detail on MART dosing.
§ DPIs contain lactose which may have small amounts of milk protein.Do you want to add Medilib to your home screen?