Reproduced with permission from: Koster A, Faraoni D, Levy JH. Antifibrinolytic therapy for cardiac surgery: An update. Anesthesiology 2015; 123(1):214-21. Copyright © 2015 American Society of Anesthesiologists, Inc. and Wolters Kluwer Health, Inc. pubs.asahq.org/anesthesiology.
References:
- Grassin-Delyle S, Couturier R, Abe E, et al. A practical tranexamic acid dosing scheme based on population pharmacokinetics in children undergoing cardiac surgery. Anesthesiology 2013; 118:853.
- Bojko B, Vuckovic D, Mirnaghi F, et al. Therapeutic monitoring of tranexamic acid concentration: High-throughput analysis with solid-phase microextraction. Ther Drug Monit 2012; 34:31.
- Grassin-Delyle S, Tremey B, Abe E, et al. Population pharmacokinetics of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass. Br J Anaesth 2013; 111:916.