Associated drug | HLA allele | Population |
Carbamazepine | B*1502 | Han Chinese, Thai, Malaysian, Singaporean, Indian, Japanese, Korean[1-7] |
B*1511 | Han Chinese, Japanese, Korean[8-9] | |
B*5701 | European[10] | |
A*31:01 (for DRESS and SJS/TEN) | European, Japanese, Korean[11-13] | |
Oxcarbazepine | B*1502 | Han Chinese, Thai[14] |
Allopurinol | B*5801 | Han Chinese[15] European[16] Japanese[17] Thai[18] Korean[19] |
Phenytoin | B*15:02 | Han Chinese, Thai, Malaysian[20] |
B*13:01 | East Asian[21] | |
B*51:01 | East Asian[22] | |
B*38:02 | Thai[23] | |
B*15:13 | Malaysian[24] | |
CYP2C9*3 | Han Chinese, Japanese, Malaysian, Thai[25] | |
Lamotrigine | B*15:02 | Han Chinese, Thai[20] |
B*38 | European[10] | |
HLA-A*31:01 | Korean[26] | |
Dapsone | B*13:01 | Southeast Asian[27] |
Sulfamethoxazole | A*29 B*38 | European[10] |
B*15:02 | Thai[28] | |
C*06-02 | Thai[28,29] | |
C*08:01 | Thai[30] | |
Methazolamide | B*59:01 | Korean/Japanese/Han Chinese[31] |
Oxicam NSAIDs | B*73 | European[10] |
Nevirapine | C*04-01 | Malawian[32] |
Strontium ranelate | A*33:03 | Han Chinese[33,34] |
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