Medications | ||
Route | Dose and frequency | |
ESAs (any of the following are acceptable) | ||
Darbepoetin alfa | SUBQ/IV |
|
Epoetin alfa | SUBQ |
|
Epoetin alfa | SUBQ |
|
Epoetin alfa | IV (in TPN) |
|
Iron | ||
Enteral iron (used in neonates tolerating enteral feeds) | ||
| PO |
|
IV iron (an option for neonates not yet tolerating enteral feeds) | ||
| IV |
|
| IV |
|
Other supplements | ||
Multivitamin | PO |
|
Folate | PO |
|
Vitamin E | PO |
|
Monitoring | ||
| ||
Treatment discontinuation | ||
|
ESA: erythropoiesis stimulating agent; SUBQ: subcutaneous; IV: intravenous; TPN: total parenteral nutrition; PO: per os (by mouth); HCT: hematocrit; Hgb: hemoglobin; ANC: absolute neutrophil count; CGA: corrected gestational age; ret-He: reticulocyte hemoglobin content; ELBW: extremely low birth weight (<1000 g); VLBW: very low birth weight (<1500 g).
* Ferrous sulfate dosing is expressed in terms of elemental iron. Ferrous sulfate oral liquid preparations contain 20% elemental iron. Multiple product concentrations exist; use caution when ordering and switching between products.
¶ A test dose of IV iron dextran is recommended prior to starting maintenance dosing.Do you want to add Medilib to your home screen?