Moderate to severe acute kidney injury (increase in serum creatinine 2 times baseline)* |
The presence of oliguria (urine output of <0.5 mL/kg per hour) for more than 6 hours, regardless of serum creatinine concentration |
Chronic kidney disease with a baseline eGFR <45 mL/minute per 1.73 m2¶ |
If baseline serum creatinine concentration is unknown:
|
In a child without a baseline creatinine concentration, a serum creatinine greater than twice the upper limit of normal for age and sex |
eGFR: estimated glomerular filtration rate.
* Kidney Disease Improving Global Outcomes (KDIGO) stage 2 or worse.
¶ Refer to UpToDate calculator for determining the eGFR; however, the creatinine used in this calculator must be a steady-state value (ie, prior to salicylate toxicity) and not a rising creatinine obtained during the course of toxicity.Do you want to add Medilib to your home screen?