This image depicts typical circuitry of V-V ECMO using a bicaval, dual-lumen, single-site approach. Blood is drained from a central vein through ports situated in the superior and inferior vena cavae (blue arrows; refer to inset). Blood is pumped through the oxygenator by a centrifugal pump and reinfused back into the right atrium (red arrows; refer to inset). The blender mixes air and oxygen to set the fraction of delivered oxygen that reaches the membrane.