Daily dose range | Low intensity | Moderate intensity | High intensity | |
Amount of LDL-C lowering | <30% | 30 to 49% | ≥50% | |
Lovastatin | 20 to 80 mg | 20 mg | 40 to 80 mg | – |
Pravastatin | 10 to 80 mg | 10 to 20 mg | 40 to 80 mg | – |
Simvastatin | 10 to 40 mg* | 10 mg | 20 to 40 mg | – |
Fluvastatin | 20 to 80 mg | 20 to 40 mg | 40 mg twice daily (or XL 80 mg once daily) | – |
Pitavastatin | 1 to 4 mg | – | 1 to 4 mg | – |
Atorvastatin | 10 to 80 mg | – | 10 to 20 mg | 40 to 80 mg |
Rosuvastatin | 5 to 40 mg | – | 5 to 10 mg | 20 to 40 mg |
LCL-C: low-density lipoprotein cholesterol; XL: extended-release 24-hour preparation.
* Although simvastatin has been used at higher doses (ie, up to 80 mg/day), we do not recommend doses >40 mg/day as there is a higher risk of myopathy, including rhabdomyolysis.Do you want to add Medilib to your home screen?