PrEP: pre-exposure prophylaxis; PEP: post-exposure prophylaxis; Ag: antigen; Ab: antibody.
* Signs and symptoms of acute HIV may include fevers, chills, rash, and/or pharyngitis. Refer to topics on Acute HIV for additional information.
¶ Additional testing with HIV RNA is warranted in persons who have recently received PrEP or PEP since the sensitivity of the antigen/antibody test may be reduced.
Δ If antigen/antibody test is positive or HIV RNA is detected at any level, PrEP should not be initiated. Such patients should be managed in consultation with a specialist in HIV care.
◊ If a rapid antigen/antibody test was performed, a laboratory-based test should be sent as well. However, PrEP does not need to be delayed pending the result of the laboratory-based test.
§ An HIV RNA test should be performed in addition to an antigen/antibody test to minimize the risk of unrecognized HIV infection, which may result in cabotegravir resistance and limit HIV treatment options.
¥ In persons with a low HIV RNA, a false positive result is possible.Do you want to add Medilib to your home screen?