Initial evaluation and management of pediatric acute disseminated encephalomyelitis (ADEM)

CBC: complete blood count; MRI: magnetic resonance imaging; MOG: myelin oligodendrocyte glycoprotein; IgG: immunoglobulin G; AQP4: aquaporin-4; IV: intravenous; IVIG: intravenous immune globulin; PLEX: plasma exchange; MOGAD: myelin oligodendrocyte glycoprotein antibody-associated disease; MS: multiple sclerosis; CNS: central nervous system; PACNS: primary angiitis of the central nervous system.

* CSF and serum testing for infections including influenza, Epstein-Barr virus (EBV), herpes, varicella, mycoplasma, cytomegalovirus, and rubella.