Underlying condition | RBC lifespan | Immune response to the virus | Effect on Hb/Hct |
None | 120 days | Normal immune response in 10 to 14 days | Normal Hb/Hct maintained |
Chronic hemolysis | 5 to 10 days | Normal immune response in 10 to 14 days | Acute transient PRCA ("aplastic crisis") |
Immunodeficiency (HIV) | 120 days | Cannot clear virus | Chronic PRCA |
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