Mandatory | Alerts | Exclusionary | |
Seizures |
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EEG |
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Age at onset |
| Age at onset <1 month or >36 months | |
Development at onset |
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Neurologic examination |
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Imaging |
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Other testing (eg, genetics) |
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Course of illness |
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Are MRI or ictal EEG required for diagnosis?
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Syndrome without laboratory confirmation: In resource-limited regions, SeLIE can be diagnosed without EEG and MRI in an infant with a family history suggestive of familial SeLIE who meets all other mandatory and exclusionary clinical criteria and has no alerts. However, the clinical history of affected family members should be consistent with the expected course for SeLIE, and careful follow-up of the patient is required to ensure their course is also consistent with this syndrome. |
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