5-ASA: 5-aminosalicylic acid; MMX: multi-matrix.
* Patients with ulcerative proctitis who responded to topical (rectal) mesalamine and who have ≤1 flare per year do not need maintenance therapy. For patients who responded to topical (rectal) mesalamine and who have >1 flare per year, we use a maintenance regimen of mesalamine suppository once daily. For patients who are unwilling to use daily topical 5-ASA therapy for long-term maintenance, we reduce the dosing frequency (eg, suppository every other day or twice weekly).
¶ Use of topical (rectal) glucocorticoids is not generally continued for >8 weeks because of the risk of systemic adverse effects.
Δ After remission is achieved with an oral 5-ASA agent, the initial dose may be continued (ie, >3 g daily), whereas decreasing the dose to 2 to 3 g daily is also a reasonable option.Do you want to add Medilib to your home screen?