Adjuvant bisphosphonates in early-stage breast cancer

* NHS PREDICT is available online at breast.predict.nhs.uk. Genomic assays, if used, can also assess risk of recurrence.

¶ Clodronate and ibandronate cannot be prescribed in the United States. Ibandronate does not have direct evidence to support a disease-free survival benefit and is less preferred than zoledronic acid or clodronate.