Risk/stage | Recurrence-free survival 5 years (%) | Time interval to transplant | Additional considerations |
Low risk
| 85 to 88 | 1 year, consider 2 years if high-risk features present | Low-risk features:
High-risk features:
Tumor deposits considered as N+ disease. Patients with stage II and III disease should complete trimodality treatment (chemoradiotherapy, surgery and chemotherapy) unless elimination of one of these is deemed appropriate after multidisciplinary discussion. For patients who have undergone preoperative radiotherapy, response to treatment is highly prognostic. Complete and nearly complete responders have much lower risk for recurrence than those with poor response. |
Low intermediate risk
| 78 to 88 | 2 years | |
High intermediate risk
| 70 | 3 years, 5 years if high-risk features present | |
High risk
| 14 | 5 years NED | SOT not recommended prior to 5 years; refer to special consideration regarding resectable CRC metastasis |
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