Skin malignancy | Appropriate treatment pretransplantation | Wait time before transplantation after treatment |
cSCC | ||
No history of SCC but at risk for development of SCC | Treatment of field disease | No delay necessary |
Low risk | Surgical excision with clear margins or Mohs micrographic surgery | No delay necessary |
High-risk SCC* (not including perineural invasion) | Surgical excision with clear margins or Mohs micrographic surgery | 2 years |
High-risk SCC with:
| Surgical excision with clear margins or Mohs micrographic surgery ± ART | 2 to 3 years |
High risk with local nodal metastatic disease | Surgical excision with appropriate lymph node dissection plus ART | 5 years |
Distant metastasis | Refer for oncology opinion | Not eligible for transplantation |
MCC | ||
Local with negative SLN biopsy | Wide local excision ± ART | 2 years |
Local with nodal metastasis | Wide local excision, lymph node dissection, ART | 3 to 5 years |
Distant metastasis | Refer for oncology opinion | Not eligible for transplantation |
MM | ||
In situ melanoma | Wide local excision | No wait necessary, follow-up posttransplantation 3 months |
Stage Ia melanoma | Wide local excision | 2 years |
Stage Ib/IIa melanoma | Wide local excision ± sentinel lymph node biopsy | 2 to 5 years |
Stage IIb/IIc melanoma | Wide local excision + sentinel lymph node biopsy | 5 years |
Any stage III or IV melanoma | Refer for oncology opinion | Not eligible for transplantation |
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