Treatment of lactotroph microadenomas in women pursuing pregnancy

PRL: prolactin.
* Cabergoline and bromocriptine are both options. Cabergoline is better tolerated and more effective than bromocriptine for lowering PRL. Reassuring pregnancy safety data are available for both drugs.
¶ Clinical evidence of ovulation includes regular intermenstrual intervals (25 to 35 days), moliminal symptoms (premenstrual breast tenderness and/or signs and symptoms of premenstrual syndrome). Biochemical evidence: day 21 serum progesterone concentration >3 ng/mL.
Δ Evaluate once a trimester for headaches and visual symptoms. Serum PRL measurements are of no diagnostic value during pregnancy.