Number | Statement |
1 | Patients should be assessed for fatigue patterns throughout their normal day to guide activity recommendations. |
1a | Patients should be assessed for their responses to initiating and escalating activity on their fatigue. |
1b | Patients should be evaluated for changes in daily functioning and activity levels. |
1c | Patients' physical functioning and endurance should be assessed to inform activity and therapy recommendations. (Examples of tests that can be chosen based on an individual's activity tolerance: 30 s sit to stand[1]; 2-min step (seated or standing)[2]; 6-min walk test[3]; 10 m walk test[4]). |
2 | Clinicians should assess for changes in activities of daily living, independent activities of daily living, school, work, and avocational (ie, hobbies). |
3 | A full patient history with review of pre-existing conditions should be conducted. |
4 | Patients should be evaluated for conditions that may exacerbate fatigue symptoms and warrant further testing and potential subspecialty referral. Particular areas include:
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5 | A medication review should be conducted to investigate medications that may be contributing to fatigue. Of note, antihistamine, anticholinergic, and antidepressant/anxiolytic medications can contribute to fatigue in patients with PASC. |
6 | The following basic laboratory workup should be considered in new patients or those without laboratory workup in the 3 months before visit including complete blood count with differential, chemistries including renal and hepatic function tests, thyroid-stimulating hormone, c-reactive protein or erythrocyte sedimentation rate, and creatinine kinase. Other laboratory tests may be considered based on the results of these tests or if there is specific concern for comorbid conditions. |
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