Patient characteristics | Studies |
All patients |
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Signs of septic shock* |
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Findings of HSV infection or at risk due to exposure (maternal active genital lesions) |
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Findings of bronchiolitis |
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High regional prevalence of influenza |
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ALT: alanine aminotransferase; aPTT: activated partial thromboplastin time; AST: aspartate aminotransferase; CBC: complete blood count; CSF: cerebrospinal fluid; COVID-19: coronavirus disease 2019; HSV: herpes simplex virus; INR: international normalized ratio; PCR: polymerase chain reaction; PT: prothrombin time; RSV: respiratory syncytial virus.
* Other causes of ill appearance in addition to sepsis include congenital heart disease, congenital adrenal hyperplasia, inborn errors of metabolism, malrotation with volvulus, and a variety of other conditions. Refer to UpToDate content on approach to the ill-appearing infant younger than 90 days of age.
¶ Serum alanine transaminase and aspartate transaminase to identify elevation in association with HSV-associated hepatitis; although these studies can also be elevated in patients with disseminated enteroviral infection or in septic shock.
Δ Do not use RSV or influenza test results to determine the need for antibiotics or antiviral agents to treat influenza in ill-appearing febrile young infants.Do you want to add Medilib to your home screen?