Adverse event | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 |
Rash maculopapular | Macules/papules covering <10% BSA with or without symptoms (eg, pruritus, burning, tightness) | Macules/papules covering 10 to 30% BSA with or without symptoms (eg, pruritus, burning, tightness); limiting instrumental ADL; rash covering >30% BSA with or without mild symptoms | Macules/papules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL | – | – |
Definition – A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbilliform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally, and associated with pruritus. |
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