The four factor prognostic model for ibrutinib assigns one point for each of the following variables: | |||
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The sum of these points determines the prognostic score, which separates patients into three risk groups with different estimated PFS and OS following treatment with single-agent ibrutinib: | |||
Score | Risk group | 3-year PFS (%) | 3-year OS (%) |
0 or 1 point | Low risk | 87 | 93 |
2 points | Intermediate risk | 74 | 83 |
3 or 4 points | High risk | 47 | 63 |
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