Adverse event | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 |
Skin and subcutaneous tissue disorders – Other, specify | Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated | Moderate; minimal, local or noninvasive intervention indicated; limiting age- appropriate instrumental ADL | Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL | Life-threatening consequences; urgent intervention indicated | Death |
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