The morphology of circulating CAR-T cells may demonstrate activated/atypical features that should not be confused with circulating malignant cells. The first three panels illustrate circulating CAR-T cells (Wright-Giemsa stain), while the panel in the lower right illustrates flow cytometry with CD3 (vertical axis) and anti-idiotype antibody specific for CTL019 (horizontal axis).
From: Brooks S, Frey N, Porter D, et al. The cytological features of CAR(T) cells. Br J Haematol 2016; 175(3):366.
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