Preterm human milk (without fortifier)*[1] | Nutrients per 100 mL of fortified preterm human milk | |||||||
Enfamil powdered HMF (bovine) 4 packets[2] | Enfamil liquid HMF standard protein (bovine) 4 vials, 20 mL[3] | Enfamil liquid HMF high protein (bovine) 4 vials, 20 mL[4] | Similac concentrated liquid HMF (bovine) 4 pouches, 20 mL[5] | Similac concentrated liquid hydrolyzed protein HMF (bovine) 4 pouches, 20 mL[6] | Prolacta +4 donor human milk-derived HMF 20 mL[7] | Prolacta +6 donor human milk-derived HMF 30 mL[7] | ||
Approximate kcal/oz, as prepared with preterm human milk* | 21 to 23 | 25.5 to 27.5 | 25 to 27 | 25 to 27 | 24.5 to 26.5 | 24.5 to 26.5 | 25.5 to 27.5 | 28 to 29.5 |
Energy (kcal/100 mL) | 70 to 77 | 84 to 91 | 83 to 89 | 83 to 89 | 82 to 88 | 82 to 88 | 85 to 90 | 92 to 97 |
Protein (g/100 mL) | 1 to 1.4 | 2.1 to 2.5 | 2.2 to 2.6 | 2.7 to 3 | 2 to 2.3 | 2.5 to 2.8 | 2 to 2.3 | 2.5 to 2.8 |
Fat (g/100 mL) | 2.6 to 3.7 | 3.6 to 4.7 | 4.1 to 5 | 4.1 to 5 | 3.1 to 4 | 2.9 to 3.8 | 4 to 4.9 | 4.6 to 5.4 |
Sodium (mg/100 mL [mEq/100 mL]) | 16 (0.7)[8] | 32 (1.4) | 36 (1.6) | 36 (1.6) | 30 (1.3) | 30 (1.3) | 49 (2.1) | 51 (2.2) |
Calcium (mg/100 mL) | 25 to 29 | 117 | 120 | 120 | 140 | 122 | 116 | 122 |
Phosphorus (mg/100 mL) | 12 to 14 | 63 | 63 | 63 | 77 | 67 | 64 | 66 |
Iron (mg/100 mL) | 0.1 | 1.5 | 1.6 | 1.6 | 0.5 | 0.5 | 0.1 | 0.1 |
Recommended targets (per kg/day)[9] | Total daily nutrients with full feeds (160 mL/kg/day) of fortified preterm human milk | |||||||
Enfamil powdered HMF (bovine) 4 packets[2] | Enfamil liquid HMF standard protein (bovine) 4 vials, 20 mL[3] | Enfamil liquid HMF high protein (bovine) 4 vials, 20 mL[4] | Similac concentrated liquid HMF (bovine) 4 pouches, 20 mL[5] | Similac concentrated liquid hydrolyzed protein HMF (bovine) 4 pouches, 20 mL[6] | Prolacta +4 donor human milk-derived HMF 20 mL[7] | Prolacta +6 donor human milk-derived HMF 30 mL[7] | ||
Energy (kcal/kg/day) | 110 to 130 | 134 to 146 | 133 to 143 | 133 to 143 | 131 to 140 | 131 to 140 | 136 to 145 | 147 to 155 |
Protein (g/kg/day) | 3.5 to 4.5 | 3.4 to 4 | 3.6 to 4.1 | 4.3 to 4.9 | 3.2 to 3.7 | 4 to 4.5 | 3.2 to 3.7 | 4 to 4.4 |
Fat (g/kg/day) | 4.8 to 6.6 | 5.8 to 7.5 | 6.6 to 8 | 6.6 to 8 | 4.9 to 6.4 | 4.6 to 6.1 | 6.4 to 7.8 | 7.4 to 8.6 |
Sodium (mg/kg/day [mEq/kg/day])¶ | 69 to 115 (3 to 5) | 51 (2.2) | 58 (2.5) | 58 (2.5) | 48 (2.1) | 48 (2.1) | 78 (3.4) | 81 (3.5) |
Calcium (mg/kg/day) | 150 to 220[10] | 187 | 190 | 190 | 222 | 196 | 186 | 195 |
Phosphorus (mg/kg/day) | 75 to 140[10] | 100 | 101 | 101 | 124 | 108 | 102 | 105 |
Iron (mg/kg/day) | 2 to 3 | 2.5 | 2.5 | 2.5 | 0.7 | 0.7 | 0.1 | 0.1 |
HMF: human milk fortifier.
* Values for macronutrient and mineral content of human milk are based on average content of mature preterm milk (ie, milk produced by a mother 5 to 12 weeks after preterm birth)[1]. The actual macronutrient content of human milk varies substantially between individuals and over the course of lactation.
¶ To convert sodium mg to mEq, divide by atomic weight of 23 or use this calculator.Do you want to add Medilib to your home screen?