Skin protectant: Topical: Apply to affected area as needed.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
Refer to adult dosing.
(For additional information see "Dimethicone (dimeticone) (topical): Pediatric drug information")
Skin protectant: Infants, Children, and Adolescents: Topical: Apply to affected area(s) as needed.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
No ADRs in manufacturer's labeling.
There are no contraindications listed in the manufacturer's labeling.
Other warnings/precautions:
• Self-medication (OTC use): For external use only. Avoid contact with eyes; flush with water with accidental contact. Do not apply to animal bites, deep puncture wounds, infected skin, or serious burns. Notify health care provider if symptoms worsen, do not improve within 7 days, or clear up and reoccur within a few days.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Cream, External:
Cavilon Durable Barrier: 1.3% (92 g [DSC]) [fragrance free, latex free; contains benzoic acid]
DermacinRx Skin Repair: 5% (118 mL) [contains cetyl alcohol, disodium edta, trolamine (triethanolamine)]
Dimopair: 5% (118 mL) [contains cetyl alcohol, edetate (edta) disodium]
Moisture Guard: 5% (85 g [DSC]) [contains methylparaben, propylparaben]
Moisturizing Skin Protectant: 8% (113 g, 198 g, 255 g) [contains cetyl alcohol, methylparaben, propylene glycol, propylparaben]
Remedy Moisture Barrier: 5% (118 mL [DSC]) [contains cetyl alcohol, edetate (edta) sodium (tetrasodium), methylparaben, propylparaben, trolamine (triethanolamine)]
Remedy Skin Repair: 1.5% (4 mL [DSC], 59 mL [DSC], 118 mL [DSC], 946 mL [DSC]) [contains cetyl alcohol, edetate (edta) sodium (tetrasodium), methylparaben, propylparaben, trolamine (triethanolamine)]
Secura Dimethicone Protectant: 5% (114 g) [fragrance free; contains disodium edta, methylparaben, propylene glycol, propylparaben]
Sween 24 Once a Day: 6% (57 g) [contains cetyl alcohol]
Liquid, External:
Restore Cleanser & Moisturizer: 2% (222 mL, 340 mL) [contains butylparaben, cetearyl alcohol, ethylparaben, isobutylparaben, methylparaben, propylparaben, trolamine (triethanolamine)]
Lotion, External:
TheraSeal Hand Protection: 1% (180 g)
May be product dependent
Cream (DermacinRx Skin Repair External)
5% (per mL): $15.55
Cream (Dimopair External)
5% (per mL): $13.05
Cream (Secura Dimethicone Protectant External)
5% (per gram): $0.09
Cream (Sween 24 Once a Day External)
6% (per gram): $0.08
Liquid (Restore Cleanser & Moisturizer External)
2% (per mL): $0.04
Lotion (TheraSeal Hand Protection External)
1% (per gram): $0.12
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Topical: For external use only; avoid contact with eyes. Formulation-specific application instructions may vary; also refer to manufacturer's labeling.
Topical: For external use only; avoid contact with eyes. Do not use on deep or puncture wounds, animal bites, or serious burns. Formulation-specific application instructions may vary; refer to manufacturer's labeling.
Skin protectant: To protect and prevent chafed, chapped, cracked, or windburned skin or lips or other minor skin irritations (eg, diaper rash, perineal dermatitis). Product-specific indications may vary; also refer to manufacturer's labeling.
Dimethicone may be confused with simethicone.
Hedrin brand name for dimethicone (topical) [United Kingdom] may be confused with Hedrin brand name for simethicone [Israel].
Baritex brand name for dimethicone (topical) [Singapore] may be confused with Barex brand name for polyethylene glycol-electrolyte solution [Argentina].
None known.
There are no known significant interactions.
Dimethicone is not absorbed systemically following topical administration (Nair 2003). Use during pregnancy would not be expected to result in significant exposure to the fetus.
Dimethicone is not absorbed systemically following topical administration (Nair 2003). Exposure via breast milk would not be expected.
Forms a protective layer on the skin that acts as a barrier to moisture loss and a protector against repeated hydration and chemical irritants.
Absorption: Little to no absorption.
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