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Multidisciplinary work-up of a patient with transthyretin amyloid cardiomyopathy
Multidisciplinary work-up of a patient with transthyretin amyloid cardiomyopathy
(A1-A3) Typical 4-chamber echocardiographic view (A1) and strain pattern (A2 and A3) characteristic of an infiltrative process.
(B1-B4) 4-chamber, steady-state, free-precession image (B1) corresponding to a 4-chamber native T1 map (B2). The corresponding LGE image (B3) shows transmural LGE, and the corresponding ECV map (B4) shows high values.
(C1-C2) Bone tracer cardiac scan (whole-body anterior
99m
Tc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy) image (C1) and single-photon emission CT image (C2) show Perugini grade 2 abnormal cardiac uptake.
LGE: late gadolinium enhancement; ECV: extracellular volume; CT: computed tomography.
Reprinted by permission from: Nature Publishing Group: Nature Reviews Cardiology. Martinez-Naharro A, Baksi AJ, Hawkins PN, Fontana M. Diagnostic imaging of cardiac amyloidosis. Nat Rev Cardiol 2020; 17:413. Copyright © 2020.
https://www.nature.com/nrcardio/
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