Evaluations and monitoring | |
Inpatients |
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Outpatients |
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Management | |
Abnormal coagulation studies |
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VTE prophylaxis |
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VTE treatment |
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Clotting in vascular catheters or extracorporeal circuits* |
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Bleeding |
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COVID-19: coronavirus disease 2019; PT: prothrombin time; aPTT: activated partial thromboplastin time; DVT: deep vein thrombosis; PE: pulmonary embolism; PERT: pulmonary embolism response team; VTE: venous thromboembolism; ICU: intensive care unit; tPA: tissue plasminogen activator; MI: myocardial infarction; ECMO: extracorporeal membrane oxygenation; DIC: disseminated intravascular coagulation.
* Includes continuous renal replacement therapy (hemodialysis), ECMO, or other extracorporeal circuits.
¶ Acute decompensated DIC is associated with clinical bleeding and/or thrombosis and laboratory findings including prolonged PT and aPTT, thrombocytopenia, and hypofibrinogenemia. Antifibrinolytic agents (tranexamic acid and epsilon aminocaproic acid) are avoided because they may tip the balance towards thrombosis. Refer to UpToDate for details.Do you want to add Medilib to your home screen?