Drug | Concentration | Initial demand dose¶ | Lockout interval | Clinician bolus dose | Continuous infusionΔ | Suggested initial 4 hour maximum (PCA demand doses and continuous infusion, if used) |
Morphine | 1 mg/mL; may use 0.5 mg/mL for patients <15 kg | 0.015 mg/kg (range 0.01 to 0.03 mg/kg) | 10 minutes | 0.02 mg/kg (range 0.02 to 0.03 mg/kg), every 20 minutes up to 3 to 4 doses within a 4 hour period, if needed | Starting dose 0.01 mg/kg/hour | 0.3 mg/kg |
Hydromorphone | 0.2 mg/mL | 0.003 mg/kg (range 0.002 to 0.006 mg/kg) | 10 minutes | 0.005 mg/kg (range 0.002 to 0.006 mg/kg) every 20 minutes up to 3 to 4 doses within a 4 hour period, if needed | Starting dose 0.002 mg/kg/hour | 0.06 mg/kg |
Fentanyl | 10 mcg/mL | 0.2 mcg/kg (range 0.1 to 0.4 mcg/kg) | 10 minutes | 0.3 mcg/kg (range 0.1 to 0.4 mcg/kg) every 20 minutes up to 3 to 4 doses within a 4 hour period, if needed | Starting dose 0.1 to 0.2 mcg/kg/hour; maximum 0.5 mcg/kg/hour up to a maximum of 25 mcg/hour◊ | 5 mcg/kg |
Do you want to add Medilib to your home screen?