NAEPP* (5 to 11 years old) | GINA (6 to 11 years old) | Our approach (4 to 11 years old) | ||
Asthma symptoms/impact | Therapy | Asthma symptoms | Therapy (all steps include SABA as needed) | Therapy |
Intermittent:
| Step 1
|
| Step 1 Preferred:
Alternatives:
| Step 1 Preferred:
Alternatives:
|
Mild persistent:
| Step 2¶ Preferred:
Alternative:
|
| Step 2 Preferred:
Alternatives:
or
| Step 2 Preferred (includes SABA as needed):
Alternatives (includes SABA as needed):
or
|
Moderate persistent:
| Step 3¶ Preferred:
Alternative:
or
|
| Step 3 Preferred:
or
Alternative:
| Step 3 Preferred:
Alternatives (includes SABA as needed):
or
or
|
Severe persistent:
| Step 4¶ Preferred:
Alternative:
or
|
| Step 4¶ Preferred:
or
Alternatives:
| Step 4 Preferred:
Alternatives (includes SABA as needed):
or
or
or
|
| Step 5 Preferred:
Alternative:
Add-on therapy:
|
| Step 5 Preferred:
Alternative add-on therapies:
| Step 5 Preferred (includes SABA as needed):
or
Alternatives (includes SABA as needed):
or
or
Add-on therapy:
|
Step 6 Preferred:
Alternative:
Add-on therapy:
| Step 6
|
NAEPP: National Asthma Education and Prevention Program; GINA: Global Initiative for Asthma; SABA: short-acting beta agonist; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; ICS: inhaled corticosteroid (glucocorticoid); LTRA: leukotriene receptor antagonist; LABA: long-acting beta agonist; OCS: oral corticosteroid (glucocorticoid); IgE: immunoglobulin E; IL-5R: interleukin 5 receptor.
* Theophylline, cromolyn, and nedocromil were not included in table even though they were included in NAEPP. They are rarely used due availability of more effective options.
¶ Subcutaneous allergen immunotherapy is suggested as adjunctive treatment in patients with well-controlled asthma and environmental allergies.Do you want to add Medilib to your home screen?