Infants ≤7 days of age | Infants 8 to 28 days of age | Infants 29 to 60 days of age | Infants and children >60 days of age | Nonpregnant adults | |
Ampicillin | Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded (weight-directed dosing)*:
| Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded (weight-directed dosing)*:
| Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded:
| Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded:
| 2 g IV every 4 hours |
or | |||||
Penicillin G | Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded:
| Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded:
| Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded:
| Patients in whom CNS infection has been documented or not yet excluded:
Patients in whom CNS infection has been excluded:
| 4 million units IV every 4 hours |
plus (if CNS, bloodstream, or other serious infection) | |||||
Infants ≤60 days of age | Infants and children >60 days of age | Nonpregnant adults | |||
Gentamicin¶ | Gestational age <30 weeks:
Gestational age 30 to 34 weeks:
Gestational age ≥35 weeks:
| 7.5 mg/kg per day IV in 3 divided doses | 5 mg/kg per day IV in 3 divided doses |
CNS: central nervous system; IV: intravenously.
* For alternative gestational age-directed dosing, refer to the pediatric drug information monograph included within UpToDate.
¶ The optimal peak gentamicin levels in listerial infection are not known; the ranges presented are the opinions of our contributors:Do you want to add Medilib to your home screen?