| <1 cm | 1 to 2 cm | >2 cm |
TNCD[1] | Cured by appendectomy if: - R0 (no tumor on margin)
- Grade 1
Right hemicolectomy if: No recommendation for tumor <1 cm, but grade 2 | Right hemicolectomy if: - Base or R1 or lymph node involvement
- Lymphovascular involvement
- Invasion of the mesoappendix >3 mm
- Grade 2
| Right hemicolectomy |
ENETS[2] | Cured by appendectomy if: Right hemicolectomy if: Discuss right hemicolectomy if: - Mesoappendix invasion >3 mm
| Right hemicolectomy if: Discuss right hemicolectomy if: - Tip/middle and R0, but with risk factors (lymphatic invasion, grade 2, or invasion of the mesoappendix >3 mm)
| Right hemicolectomy |
UKINETS[3] | Cured by appendectomy | Right hemicolectomy if: - Serosal breach by tumor
- Cellular atypia
- Mesoappendix invasion >3 mm
- Base (perforation of the appendix) (lymphovascular and perineural invasion)
| Right hemicolectomy |
NCCN[4] | Cured by appendectomy if: - Confined to the appendix (complete resection: nodes, margins)
| Right hemicolectomy |
NANETS[5] | Cured by appendectomy if: - Tip
- Complete tumor resection
- No lymphovascular involvement
- No invasion of the mesoappendix
| Right hemicolectomy if: - Base
- Incomplete tumor resection
- Lymphovascular invasion
- Mesoappendix invasion
- Intermediate- to high-grade tumor
- Mesenteric nodal involvement
| Right hemicolectomy |