Dengue and Zika virus NAATs | Interpretation | |||
Positive dengue virus assay, negative Zika virus assay | Acute dengue virus infection | |||
Positive Zika virus assay, negative dengue virus assay | Acute Zika virus infection | |||
Positive (both assays) | Acute dengue and Zika virus coinfection | |||
Negative (both assays) | No evidence of dengue or Zika virus infection* | |||
Dengue and Zika virus IgM antibodies | Dengue virus PRNT | Zika virus PRNT | Nonpregnant patients | Pregnant women |
Positive (either assay)¶Δ | ≥10 | <10 | Recent dengue virus infection | Dengue virus infection, timing cannot be determined |
Positive (either assay)¶Δ | <10 | ≥10 | Recent Zika virus infection | Zika virus infection, timing cannot be determined |
Positive (either assay)¶ | ≥10 | ≥10 | Recent flavivirus infection◊ | Flavivirus infection, timing cannot be determined |
Any result | <10 | <10 | No evidence of dengue or Zika virus infection§ | No evidence of dengue or Zika virus infection§ |
Positive dengue virus assay, negative Zika virus assay | Not performed | Presumptive recent dengue virus infection | Presumptive dengue virus infection, timing cannot be determined | |
Positive Zika virus assay, negative dengue virus assay | Not performed | Presumptive recent Zika virus infection | Presumptive Zika virus infection, timing cannot be determined | |
Positive (both assays) | Not performed | Presumptive recent flavivirus infection◊ | Presumptive flavivirus infection, timing cannot be determined | |
Positive dengue virus assay, Zika virus assay not performed | Not performed | Presumptive recent flavivirus infection◊ | Presumptive flavivirus infection, timing cannot be determined | |
Positive Zika virus assay, dengue virus assay not performed | Not performed | Presumptive recent flavivirus infection◊ | Presumptive flavivirus infection, timing cannot be determined | |
Negative (both assays) | Not performed | No evidence of dengue or Zika virus infection§ | No evidence of dengue or Zika virus infection§ | |
Negative dengue virus assay, Zika virus assay not performed | Not performed | No evidence of dengue virus infection§ | No evidence of dengue virus infection§ | |
Negative Zika virus assay, dengue virus assay not performed | Not performed | No evidence of Zika virus infection§ | No evidence of Zika virus infection§ |
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