Algorithm for initial staging of rhabdomyosarcoma

CT: computed tomography; FOXO1: forkhead box protein O1; PAX: paired box protein.

* Unfavorable histology: alveolar histology or PAX-FOXO1 fusion.

¶ Full metastatic workup includes chest CT, bone scan, and bilateral bone marrow examination.

Original algorithm modified for this publication. Reproduced with permission from: Weiss AR, Lyden ER, Anderson JR, et al. Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue sarcoma Committee. J Clin Oncol 2013; 31(26):3226-3232. Copyright © 2013 American Society of Clinical Oncology. https://ascopubs.org/journal/jco.

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Algorithm for initial staging of rhabdomyosarcoma