Referral to a lung transplant center is recommended at or before any of the following milestones are reached: |
Patients ≥18 years |
FEV1 <50% predicted and rapidly declining (eg, >20% relative decline in FEV1 within 12 months) |
FEV1 <40% predicted and*:
|
FEV1 <30% predicted |
Patients <18 years |
FEV1 <50% predicted and rapidly declining (eg, >20% relative decline in FEV1 within 12 months) |
FEV1 <50% predicted with any marker of shortened survival listed above or malnutrition (BMI <10th percentile, while working to improve nutritional status) |
FEV1 <40% predicted* |
All patients |
Any of the following, regardless of FEV1:
|
Other factors that warrant earlier consideration for transplant referral, even when other thresholds have not been met |
Female sex, especially those who are younger |
Short stature (height <162 cm)¶ |
Liver cirrhosis or chronic kidney disease (may require consideration of multiple organ transplantation and may affect timing or choice of transplant center) |
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