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Lymphatic and melanocytic markers in lymphangioleiomyomatosis

Lymphatic and melanocytic markers in lymphangioleiomyomatosis
(A-D) Lung biopsy samples showing positive immunoreactivity for the lymphatic marker, D2-40 (podoplanin; A), for the melanocytic marker human melanoma black-45 (HMB-45; B) and for the smooth muscle marker smooth muscle actin (SMA; C). Staining for hematoxylin and eosin (H&E) is also shown (D).
Reprinted with the permission of the American Thoracic Society. Copyright © 2019 American Thoracic Society. Badri KR, Gao L, Hyjek E, et al. Exonic mutations of TSC2/TSC1 are common but not seen in all sporadic pulmonary lymphangioleiomyomatosis. Am J Respir Crit Care Med 2013; 187:663-665. The American Journal of Respiratory and Critical Care Medicine is an official journal of the American Thoracic Society.
Graphic 120922 Version 2.0