Low risk for bleeding | High risk for bleeding | ||||||
DTI | Factor Xa inhibitor | DTI | Factor Xa inhibitor | ||||
CrCl | Discontinue | CrCl | Discontinue | CrCl | Discontinue | CrCl | Discontinue |
<15 | No data, ≥96 hours | <15 | No data, ≥48 hours | <15 | No data | <30 | No data, ≥72 hours |
15 to 29 | ≥72 hours | 15 to 29 | ≥36 hours | 15 to 29 | ≥120 hours | ≥30 | ≥48 hours |
30 to 49 | ≥48 hours | ≥30 | ≥24 hours | 30 to 49 | ≥96 hours | ||
50 to 79 | ≥36 hours | 50 to 79 | ≥72 hours | ||||
≥80 | ≥24 hours | ≥80 | ≥48 hours |
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