Platelet count | Likelihood of GT |
100,000 to 149,000/microL | - Almost certainly GT (in our cohort of 4568 individuals with uncomplicated pregnancies, 99% had platelet counts ≥100,000/microL at delivery; among the 450 who were diagnosed with GT, 93% had platelet counts between 100,000 and 149,000/microL).
- ITP cannot be excluded but is very unlikely.
- Other diagnoses are also very unlikely.
|
80,000 to 99,000/microL | - Probably not GT (in our cohort of 4568 individuals with uncomplicated pregnancies, only 26 [0.6%] had platelet counts between 80,000 and 99,000/microL at delivery).
- Other causes of thrombocytopenia should be considered, such as ITP, pseudothrombocytopenia due to platelet clumping, and hereditary thrombocytopenia.
|
60,000 to 79,000/microL | - Almost certainly not GT (in our cohort of 4568 individuals with uncomplicated pregnancies, only 12 [0.3%] had platelet counts between 60,000 and 79,000/microL at any time. Only 5 had GT; 7 had another diagnosis [7 platelet count error; 2 unrecognized ITP; 1 unrecognized hereditary thrombocytopenia]).
- Almost certainly there is another cause for the thrombocytopenia. If the diagnosis of ITP is considered, no treatment would be required.
|
<60,000/microL | - Not GT (none of 450 individuals with GT in our study had a platelet count <60,000/microL).
- Another cause for the thrombocytopenia must be identified. Treatment of ITP would be required if the platelet count is <30,000/microL.
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