Version October 2024
Ocular irrigation: Infants, Children, and Adolescents: Ophthalmic: Based on standard for each surgical procedure.
There are no dosage adjustments provided in manufacturer's labeling.
There are no dosage adjustments provided in manufacturer's labeling.
(For additional information see "Balanced salt solution: Drug information")
Ocular irrigation: Ophthalmic: Based on standard for each surgical procedure.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Frequency not defined.
Ophthalmic: Corneal decompensation, corneal edema, corneal opacity, ophthalmic inflammation
There are no contraindications listed in the manufacturer labeling
Disease-related concerns:
• Diabetes: Use with caution in patients with diabetes mellitus; intraoperative lens changes have been observed when undergoing vitrectomy procedure.
Dosage form specific issues:
• BSS Plus: Do not use unless Part I of the product is fully reconstituted with Part II.
Other warnings/precautions:
• Appropriate use: Not for injection or IV infusion.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution, ophthalmic [irrigation; preservative free]:
BSS: Sodium chloride 0.64%, potassium chloride 0.075%, calcium chloride 0.048%, magnesium chloride 0.03%, sodium acetate 0.39%, sodium citrate 0.17% (15 mL, 30 mL, 250 mL, 500 mL)
BSS Plus: Sodium chloride 0.71%, potassium chloride 0.038%, calcium chloride 0.015%, magnesium chloride 0.02%, sodium phosphate 0.042%, sodium bicarbonate 0.21%, dextrose 0.092%, glutathione 0.018% (250 mL, 500 mL)
No
Solution (Optics Eye Wash Ophthalmic)
0.9% (20 mL): $0.24
Disclaimer: The pricing data provide a representative AWP and/or AAWP price from a single manufacturer of the brand and/or generic product, respectively. The pricing data should be used for benchmarking purposes only, and as such should not be used to set or adjudicate any prices for reimbursement or purchasing functions. Pricing data is updated monthly.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution, ophthalmic [irrigation]:
BSS: Sodium chloride 0.64%, potassium chloride 0.075%, calcium chloride 0.048%, magnesium chloride 0.03%, sodium acetate trihydrate 0.39%, sodium citrate dihydrate 0.17%
BSS Plus: Sodium chloride 0.714%, potassium chloride 0.038%, calcium chloride 0.0154%, magnesium chloride 0.2%, sodium phosphate dibasic 0.042%, sodium bicarbonate 0.21%, dextrose 0.092%, glutathione disulfide 0.0184%
Ophthalmic: Not for injection or IV infusion. For administration by surgeon in surgical suite. Do not use if discolored or contains a precipitate.
BSS Plus: Use an administration set with an air-inlet in the plastic spike (bottle does not contain separate airway tube). Allow fluid to freely flow to remove air from the tubing prior to irrigation. If a second bottle of reconstituted BSS Plus is needed to complete a surgical procedure, vent vacuum in the second bottle prior to attachment to the administration set.
Ophthalmic: Not for injection or IV infusion. Do not use if discolored or contains a precipitate.
BSS: Attach surgeon’s sterile irrigating needle to adapter plug. Squeeze out several drops before inserting into anterior eye chamber. Remove needle from anterior eye chamber before releasing pressure to prevent suction. External irrigation may be done without irrigating needle. Discard any unused portion.
BSS Plus: Use an administration set with an air inlet in the plastic spike (bottle does not contain separate airway tube). Allow fluid to freely flow to remove air from the tubing prior to irrigation. If a second bottle of reconstituted BSS Plus is needed to complete a surgical procedure, vent vacuum in the second bottle prior to attachment to the administration set. Discard any unused portion within 6 hours of preparation.
Store at 2°C to 25°C (36°F to 77°F); do not freeze.
BSS Plus: Discard prepared solution after 6 hours.
Irrigation during various intraocular surgical procedures involving perfusion of the eye (BSS: Procedure <1 hour; BSS Plus: procedures of any duration) (FDA approved in pediatric patients [age not specified] and adults).
None known.
Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the drug interactions program
There are no known significant interactions.
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