Infants (birth to 1 year) | - The vaccination series should be started as soon as possible after birth, preferably within 12 hours.*
- For infants born to mothers who are HBsAg positive, HBIG should be administered at the same time as the birth dose HBV vaccine (at a different anatomic site).
- For infants born to mothers who are HBsAg positive and mothers whose HBsAg status cannot be determined, obtain HBsAg and anti-HBs after completion of HBV vaccination series (usually at age 9 to 12 months). Revaccination may be necessary.
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Unvaccinated persons age ≥60 years who are at increased risk for acquiring HBV or developing severe HBV infection as well as those who wish to be vaccinated This includes individuals with: - Chronic liver disease
- HIV infection
- HCV infection
- Percutaneous or mucosal risk for HBV exposure (eg, injection drug use, occupational risk, household contact of someone with HBsAg)
- Sexual risk for HBV (eg, sexual contact with someone who is HBsAg positive, persons who are sexually active and not in mutually monogamous relationships)
- Planned travel to countries with high (≥8%) or intermediate (2 to 7%) endemic prevalence of HBV infection
- Risk due to being incarcerated
- Risk due to working or living in facilities for persons who are developmentally disabled
- Persons who are predialysis or are undergoing hemodialysis, peritoneal dialysis, or home dialysis
| - Among individuals who are at increased risk for HBV, post-vaccination serologic testing (anti-HBs) is warranted for certain groups (eg, those with HIV, health care and public safety personnel, persons who are predialysis or are undergoing dialysis, and sexual partners of persons who are HBsAg positive).
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