Cutaneous plaques in progestogen hypersensitivity

Patient was seen with round, 1 to 2 cm, dark, erythematous, scaly plaques on her face, neck, abdomen, chest, pelvis, and lower back, which slowly faded to a dark-purple color but did not clear entirely before the start of her next cycle, when a new crop would appear at the same anatomic location. The previous month, she also had lip and eyelid swelling and an oral mucosa lesion. Skin lesions in 2 consecutive months are shown.