Term | Clinical findings | Histopathological findings[1] |
Myalgia | Unexplained muscle discomfort often described as "flu-like" symptoms with normal CK level The spectrum of myalgia complaints includes:
| None |
Myopathy | Muscle weakness (not attributed to pain and not necessarily associated with elevated CK) | Variable findings:
|
Myositis | Muscle inflammation | T cells > B cells; macrophages |
Myonecrosis | Muscle enzyme elevations or hyperCKemia
| Non-specific inflammatory cells with secondary macrophage infiltration |
Myonecrosis with myoglobinuria (rhabdomyolysis) | Increase in serum creatinine ≥0.5 mg/dL (clinical rhabdomyolysis) | Non-specific inflammatory cells with secondary macrophage infiltration |
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