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Anti-Xa (units/mL) | aPTT (seconds) | Bolus (units/kg) | Hold infusion (minutes) | Rate change | Repeat anti-Xa/aPTT |
≤0.1 | <50 | 50 | 0 | Increase 10% | 4 hours |
0.11 to 0.34 | 50 to 59 | 0 | 0 | Increase 10% | 4 hours |
0.35 to 0.7 | 60 to 85 | 0 | 0 | No change | 4 hours, then daily once 2 consecutive values are in range |
0.71 to 0.99 | 86 to 95 | 0 | 0 | Decrease 10% | 4 hours |
1.0 to 1.19 | 96 to 120 | 0 | 30 | Decrease 10% | 4 hours |
≥1.2 | >120 | 0 | 60 | Decrease 15% | 4 hours |
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