Antimicrobial agent | Regimen[1-5] |
Parenteral therapy | |
Cefazolin |
|
Ceftaroline |
|
Ceftriaxone |
|
Clindamycin |
|
Dalbavancin |
|
Daptomycin |
|
Linezolid |
|
Nafcillin |
|
Oxacillin |
|
Tedizolid |
|
Vancomycin |
|
Oral therapy | |
Amoxicillin |
|
Cefadroxil |
|
Cefuroxime |
|
Cephalexin |
|
Clindamycin |
|
Cloxacillin (not available in the United States) |
|
DoxycyclineΔ |
|
Linezolid |
|
Penicillin V |
|
Tedizolid |
|
TMP-SMX |
|
AUC: area under the curve; IV: intravenous; MSSA: methicillin-susceptible S. aureus; SSTI: skin and soft tissue infection; TMP-SMX: trimethoprim-sulfamethoxazole.
* The approach to vancomycin dosing is generally determined at the institutional level. Refer to UpToDate content on invasive staphylococcal infections in children for details of trough-guided and AUC-guided vancomycin dosing.
¶ Use doses on the higher end of the range for more severe infection or when MSSA is suspected.[6]
Δ Tetracycline antibiotics may cause permanent tooth discoloration for children <8 years if used repeatedly. However, doxycycline binds less readily to calcium than other tetracyclines and may be used for ≤21 days in children of all ages.[7]Do you want to add Medilib to your home screen?