Local anesthetic | Dose (mg) | Peak cephalad block height | Time to two-segment regression (1 SD or range) (minutes)* | Recommended time interval for top-up dose (minutes)¶ |
Chloroprocaine 2 to 3% plus 1:200,000 epinephrine[1,2] | 600 | T5 | 80 (15) | 45 |
Lidocaine 1.5 to 2% plus 1:200,000 epinephrine[2,3] | 300 to 400 | T4 | 100 (50 to 60) | 60 |
Bupivacaine 0.5 to 0.75% (plain)[4,5] | 100 to 150 | T5 | 150 to 190 (60 to 80) | 120 |
Ropivacaine 1% (plain)[6] Age 30 (18 to 40)Δ | 150 | T8◊ | 143 (45 to 298) | 120 |
Ropivacaine 1% (plain)[6] Age 51 (41 to 59)Δ | 150 | T6 | 190 (100 to 340) | 120 |
Ropivacaine 1% (plain)[6] Age 71 (61 to 82)Δ | 150 | T4◊ | 203 (105 to 378) | 120 |
Levobupivacaine 0.75% (plain)[7] Age 32 (18 to 44)Δ | 125 | T8◊ | 166 (51) | 120 |
Levobupivacaine 0.75% (plain)[7] Age 57 (47 to 69)Δ | 125 | T5 | 158 (59) | 120 |
Levobupivacaine 0.75% (plain)[7] Age 78 (72 to 85)Δ | 125 | T5◊ | 174 (61) | 120 |
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